AmiGO 2: Term Details for "thymidylate synthase (FAD) activity" (GO:0050797)

Accession: GO:0050797
Name: thymidylate synthase (FAD) activity
Ontology: molecular_function
Synonyms: Thy1 activity, ThyX activity, 5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase activity, FDTS activity, flavin dependent thymidylate synthase activity
Alternate IDs: None
Definition: Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+. Source: EC:2.1.1.148
Comment: None
History: See term history for GO:0050797 at QuickGO
Chem. react.: has participant NADPH(4-); has participant dTMP(2-); has participant NADP(3-); has participant (6S)-5,6,7,8-tetrahydrofolate(2-); has participant dUMP(2-); has participant hydron; has participant (6R)-5,10-methylenetetrahydrofolate(2-)
Subset: None
Related: Link to all genes and gene products annotated to thymidylate synthase (FAD) activity (excluding "regulates").; Link to all direct and indirect annotations to thymidylate synthase (FAD) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for thymidylate synthase (FAD) activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
thymidylate synthase (FAD) activity	RO:0000057	NADPH(4-) (CHEBI:57783)
thymidylate synthase (FAD) activity	is_a	5,10-methylenetetrahydrofolate-dependent methyltransferase activity (GO:0042083)
thymidylate synthase (FAD) activity	RO:0000057	dTMP(2-) (CHEBI:63528)
thymidylate synthase (FAD) activity	RO:0000057	NADP(3-) (CHEBI:58349)
thymidylate synthase (FAD) activity	RO:0000057	(6S)-5,6,7,8-tetrahydrofolate(2-) (CHEBI:57453)
thymidylate synthase (FAD) activity	RO:0000057	dUMP(2-) (CHEBI:246422)
thymidylate synthase (FAD) activity	RO:0000057	hydron (CHEBI:15378)
thymidylate synthase (FAD) activity	RO:0000057	(6R)-5,10-methylenetetrahydrofolate(2-) (CHEBI:15636)

This term has no children.