obsolete deoxyhypusine biosynthetic process from spermidine
Ontology
biological_process
Synonyms
deoxyhypusine anabolism from spermidine, using deoxyhypusine synthase, deoxyhypusine biosynthesis from spermidine, using deoxyhypusine synthase, deoxyhypusine biosynthetic process from spermidine, using deoxyhypusine synthase, deoxyhypusine formation from spermidine, using deoxyhypusine synthase, spermidine breakdown to deoxyhypusine, using deoxyhypusine synthase, spermidine catabolic process to deoxyhypusine, using deoxyhypusine synthase, spermidine degradation to deoxyhypusine, using deoxyhypusine synthase
Alternate IDs
None
Definition
OBSOLETE. The chemical reactions resulting in the formation of deoxyhypusine from spermidine by the enzyme [eIF-5A]-deoxyhypusine synthase. The reaction occurs in four steps: 1. spermidine + NAD+ = dehydrospermidine + NADH + H+; 2. dehydrospermidine + [enzyme]-lysine = 1,3-diaminopropane + [enzyme]-lysine-N6=CH(CH2)3NH2; 3. [enzyme]-lysine-N6=CH(CH2)3NH2 = [eIF-5A]-lysine-N6=CH(CH2)3NH2; 4. [eIF-5A]-lysine-N6=CH(CH2)3NH2 + NADH + H+ = [eIF-5A]-deoxyhypusine + NAD+.
Source:MetaCyc:1.1.1.249-RXN
Comment
The reason for obsoletion is that although GO:0050983 is described as a multistep process, the entire reaction is carried out by a single enzyme, therefore was replacey by the molecular function GO:0034038 deoxyhypusine synthase activity.
Link
to all genes and gene products annotated to obsolete deoxyhypusine biosynthetic process from spermidine (excluding "regulates").
Link
to all direct and indirect annotations
to obsolete deoxyhypusine biosynthetic process from spermidine (excluding "regulates").
Link
to all direct and indirect annotations download (limited to first 10,000)
for obsolete deoxyhypusine biosynthetic process from spermidine (excluding "regulates").
