AmiGO 2: Term Details for "G-quadruplex DNA binding" (GO:0051880)

Accession: GO:0051880
Name: G-quadruplex DNA binding
Ontology: molecular_function
Synonyms: G quadruplex DNA binding, G quartet DNA binding, G-DNA binding, G-quartet DNA binding, quadruplex DNA binding, tetraplex DNA binding, G quartet binding, G-quartet binding
Alternate IDs: None
Definition: Binding to G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome. Source: PMID:16142245, PMID:9512530
Comment: None
History: See term history for GO:0051880 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to G-quadruplex DNA binding (excluding "regulates").; Link to all direct and indirect annotations to G-quadruplex DNA binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for G-quadruplex DNA binding (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
G-quadruplex DNA binding	is_a	DNA binding (GO:0003677)

subject	relation	object
negative regulation of G-quadruplex DNA binding (GO:1905494)	RO:0002212	G-quadruplex DNA binding
telomeric G-quadruplex DNA binding (GO:0061849)	is_a	G-quadruplex DNA binding
positive regulation of G-quadruplex DNA binding (GO:1905495)	RO:0002213	G-quadruplex DNA binding
regulation of G-quadruplex DNA binding (GO:1905493)	RO:0002211	G-quadruplex DNA binding

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