AmiGO 2: Term Details for "peroxiredoxin activity" (GO:0051920)

Accession: GO:0051920
Name: peroxiredoxin activity
Ontology: molecular_function
Synonyms: PRDX activity, Prx activity
Alternate IDs: None
Definition: Catalysis of the reaction: [protein]-dithol + ROOH = [protein]-disulfide + H2O + ROH. Source: RHEA:10008
Comment: Includes redox chemistry as part of the catalytic reaction (2 R'-SH = R'-S-S-R'), where R' refers to peroxiredoxin itself). Not to be confused with GO:0004601 (peroxidase activity, EC:1.11.1.7), which has a different reaction mechanism.
History: See term history for GO:0051920 at QuickGO
Chem. react.: has participant L-cystine residue; has participant L-cysteine residue; has participant alcohol; has participant water; has participant peroxol
Subset: None
Related: Link to all genes and gene products annotated to peroxiredoxin activity (excluding "regulates").; Link to all direct and indirect annotations to peroxiredoxin activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for peroxiredoxin activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
thioredoxin-dependent peroxiredoxin activity (GO:0140824)	is_a	peroxiredoxin activity
NADH-dependent peroxiredoxin activity (GO:0102039)	is_a	peroxiredoxin activity