AmiGO 2: Term Details for "lysine biosynthetic process via alpha-aminoadipate and saccharopine" (GO:0051975)

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Term Information

Accession: GO:0051975
Name: lysine biosynthetic process via alpha-aminoadipate and saccharopine
Ontology: biological_process
Synonyms: lysine biosynthesis via aminoadipic acid and saccharopine, lysine biosynthetic process via aminoadipic acid and saccharopine
Alternate IDs: None
Definition: The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine. Source: MetaCyc:LYSINE-AMINOAD-PWY
Comment: None
History: See term history for GO:0051975 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to lysine biosynthetic process via alpha-aminoadipate and saccharopine (excluding "regulates").; Link to all direct and indirect annotations to lysine biosynthetic process via alpha-aminoadipate and saccharopine (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for lysine biosynthetic process via alpha-aminoadipate and saccharopine (excluding "regulates").

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0071704 organic substance metabolic process
GO:0044281 small molecule metabolic process
GO:0006520 amino acid metabolic process
GO:0044249 cellular biosynthetic process
GO:0006082 organic acid metabolic process
GO:1901576 organic substance biosynthetic process
GO:0044283 small molecule biosynthetic process
GO:1901605 alpha-amino acid metabolic process
GO:0008652 amino acid biosynthetic process
GO:0046394 carboxylic acid biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0016053 organic acid biosynthetic process
GO:1901566 organonitrogen compound biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0043436 oxoacid metabolic process
GO:0044238 primary metabolic process
GO:1901607 alpha-amino acid biosynthetic process
GO:0170033 L-amino acid metabolic process
GO:0170039 proteinogenic amino acid metabolic process
GO:0009066 aspartate family amino acid metabolic process
GO:0170034 L-amino acid biosynthetic process
GO:0170038 proteinogenic amino acid biosynthetic process
GO:0009067 aspartate family amino acid biosynthetic process
GO:0006553 lysine metabolic process
GO:0009085 lysine biosynthetic process
GO:0019878 lysine biosynthetic process via aminoadipic acid
GO:0051975 lysine biosynthetic process via alpha-aminoadipate and saccharopine
GO:2001195 negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine
GO:2001196 positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine
GO:2001194 regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine

Parents of lysine biosynthetic process via alpha-aminoadipate and saccharopine (GO:0051975)

subject	relation	object
lysine biosynthetic process via alpha-aminoadipate and saccharopine	is_a	lysine biosynthetic process via aminoadipic acid (GO:0019878)
lysine biosynthetic process via alpha-aminoadipate and saccharopine	RO:0002505	2-aminoadipic acid (CHEBI:37024)
lysine biosynthetic process via alpha-aminoadipate and saccharopine	RO:0004008	lysinium(1+) (CHEBI:32564)
lysine biosynthetic process via alpha-aminoadipate and saccharopine	RO:0002505	L-saccharopinate(1-) (CHEBI:57951)

Children of lysine biosynthetic process via alpha-aminoadipate and saccharopine (GO:0051975)

subject	relation	object
regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine (GO:2001194)	RO:0002211	lysine biosynthetic process via alpha-aminoadipate and saccharopine
negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine (GO:2001195)	RO:0002212	lysine biosynthetic process via alpha-aminoadipate and saccharopine
positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine (GO:2001196)	RO:0002213	lysine biosynthetic process via alpha-aminoadipate and saccharopine

MetaCyc: LYSINE-AMINOAD-PWY