Term Information

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Accession
GO:0052707
Name
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine
Ontology
biological_process
Synonyms
hercynine biosynthesis from histidine, histidine betaine biosynthesis from histidine, histidine catabolic process to hercynine, histidine catabolism to N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, histidine catabolism to hercynine
Alternate IDs
None
Definition
The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). Source: EC:2.1.1.44
Comment
None
History
See term history for GO:0052707 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine (GO:0052707)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [BFO:0000051 relation] BFO:0000051  dimethylhistidine N-methyltransferase activity (GO:0030745)
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [is_a relation] is_a  N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process (GO:0052709)
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [BFO:0000051 relation] BFO:0000051  histidine N-methyltransferase activity (GO:0052706)
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [BFO:0000051 relation] BFO:0000051  methylhistidine N-methyltransferase activity (GO:0052705)
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [is_a relation] is_a  histidine catabolic process (GO:0006548)
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [RO:0004008 relation] RO:0004008  N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine (CHEBI:15781)
N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine [RO:0004009 relation] RO:0004009  histidinate(1-) (CHEBI:32529)

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KEGG_REACTION
R01169