AmiGO 2: Term Details for "DNA-3-methylguanine glycosylase activity" (GO:0052822)

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Term Information

Accession: GO:0052822
Name: DNA-3-methylguanine glycosylase activity
Ontology: molecular_function
Synonyms: 3-methylguanine DNA glycosylase I, DNA glycosidase I activity, deoxyribonucleate 3-methylguanine glycosidase I, alkylated-DNA glycohydrolase (releasing methyladenine and methylguanine)
Alternate IDs: None
Definition: Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site. Source: PMID:9224623, PMID:10872450, EC:3.2.2.21, GOC:elh
Comment: None
History: See term history for GO:0052822 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DNA-3-methylguanine glycosylase activity (excluding "regulates").; Link to all direct and indirect annotations to DNA-3-methylguanine glycosylase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DNA-3-methylguanine glycosylase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0016787 hydrolase activity
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0140097 catalytic activity, acting on DNA
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
GO:0019104 DNA N-glycosylase activity
GO:0003905 alkylbase DNA N-glycosylase activity
GO:0043733 DNA-3-methylbase glycosylase activity
GO:0052822 DNA-3-methylguanine glycosylase activity

Parents of DNA-3-methylguanine glycosylase activity (GO:0052822)

subject	relation	object
DNA-3-methylguanine glycosylase activity	is_a	DNA-3-methylbase glycosylase activity (GO:0043733)

This term has no children.

EC: 3.2.2.21
MetaCyc: 3.2.2.21-RXN