AmiGO 2: Term Details for "large conductance calcium-activated potassium channel activity" (GO:0060072)

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Term Information

Accession: GO:0060072
Name: large conductance calcium-activated potassium channel activity
Ontology: molecular_function
Synonyms: BK KCa channel activity, BK calcium-activated potassium channel activity, large conductance KCa channel activity, BK channel activity
Alternate IDs: GO:0022895
Definition: Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Source: GOC:mtg_transport, ISBN:0815340729, PMID:17115074
Comment: None
History: See term history for GO:0060072 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to large conductance calcium-activated potassium channel activity (excluding "regulates").; Link to all direct and indirect annotations to large conductance calcium-activated potassium channel activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for large conductance calcium-activated potassium channel activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0051179 localization
GO:0051234 establishment of localization
GO:0009987 cellular process
GO:0003674 molecular_function
GO:0006810 transport
GO:0006811 monoatomic ion transport
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0005215 transporter activity
GO:0015267 channel activity
GO:0098660 inorganic ion transmembrane transport
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0030001 metal ion transport
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0022803 passive transmembrane transporter activity
GO:0022836 gated channel activity
GO:0098662 inorganic cation transmembrane transport
GO:0022890 inorganic cation transmembrane transporter activity
GO:0022834 ligand-gated channel activity
GO:0098655 monoatomic cation transmembrane transport
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0005216 monoatomic ion channel activity
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0006813 potassium ion transport
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0046873 metal ion transmembrane transporter activity
GO:0005261 monoatomic cation channel activity
GO:0071805 potassium ion transmembrane transport
GO:0099094 ligand-gated monoatomic cation channel activity
GO:0022839 monoatomic ion-gated channel activity
GO:0015079 potassium ion transmembrane transporter activity
GO:0005227 calcium-activated cation channel activity
GO:0005267 potassium channel activity
GO:0015269 calcium-activated potassium channel activity
GO:0060072 large conductance calcium-activated potassium channel activity
GO:1902607 negative regulation of large conductance calcium-activated potassium channel activity
GO:1902608 positive regulation of large conductance calcium-activated potassium channel activity
GO:1902606 regulation of large conductance calcium-activated potassium channel activity

Parents of large conductance calcium-activated potassium channel activity (GO:0060072)

subject	relation	object
large conductance calcium-activated potassium channel activity	is_a	calcium-activated potassium channel activity (GO:0015269)

Children of large conductance calcium-activated potassium channel activity (GO:0060072)

subject	relation	object
regulation of large conductance calcium-activated potassium channel activity (GO:1902606)	RO:0002211	large conductance calcium-activated potassium channel activity
positive regulation of large conductance calcium-activated potassium channel activity (GO:1902608)	RO:0002213	large conductance calcium-activated potassium channel activity
negative regulation of large conductance calcium-activated potassium channel activity (GO:1902607)	RO:0002212	large conductance calcium-activated potassium channel activity

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