Term Information

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Accession
GO:0061542
Name
3-demethylubiquinol-n 3-O-methyltransferase activity
Ontology
molecular_function
Synonyms
OMHMB-methyltransferase, S-adenosyl-L-methionine:2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone-O-methyltransferase, 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase, 5-demethylubiquinone-10 methyltransferase, 5-demethylubiquinone-9 methyltransferase
Alternate IDs
None
Definition
Catalysis of the reaction: S-adenosyl-L-methionine + a 3-demethylubiquinol = S-adenosyl-L-homocysteine + a ubiquinol. Source: PMID:23190198, GOC:dph, PMID:10777520, RHEA:44380
Comment
Note that the polyprenyl sidechain substrate for this reaction has a different number of prenyl units in different organisms (for example, ubiquinone-6 in Saccharomyces, ubiquinone- 9 in rat and ubiquinone-10 in human), and thus the natural substrate for the enzymes from different organisms has a different number of prenyl units. However, the enzyme usually shows a low degree of specificity regarding the number of prenyl units.
History
See term history for GO:0061542 at QuickGO
Chem. react.
has participant 3-demethylubiquinol
has participant S-adenosyl-L-homocysteine zwitterion
has participant S-adenosyl-L-methionine zwitterion
has participant ubiquinol
has participant hydron
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0061542 from QuickGO

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Parents of 3-demethylubiquinol-n 3-O-methyltransferase activity (GO:0061542)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
3-demethylubiquinol-n 3-O-methyltransferase activity [RO:0000057 relation] RO:0000057  3-demethylubiquinol (CHEBI:84422)
3-demethylubiquinol-n 3-O-methyltransferase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-homocysteine zwitterion (CHEBI:57856)
3-demethylubiquinol-n 3-O-methyltransferase activity [is_a relation] is_a  S-adenosylmethionine-dependent methyltransferase activity (GO:0008757)
3-demethylubiquinol-n 3-O-methyltransferase activity [is_a relation] is_a  O-methyltransferase activity (GO:0008171)
3-demethylubiquinol-n 3-O-methyltransferase activity [RO:0000057 relation] RO:0000057  S-adenosyl-L-methionine zwitterion (CHEBI:59789)
3-demethylubiquinol-n 3-O-methyltransferase activity [RO:0000057 relation] RO:0000057  ubiquinol (CHEBI:17976)
3-demethylubiquinol-n 3-O-methyltransferase activity [BFO:0000050 relation] BFO:0000050  ubiquinone biosynthetic process (GO:0006744)
3-demethylubiquinol-n 3-O-methyltransferase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)

This term has no children.

EC
2.1.1.64
Reactome
R-HSA-2162186
RHEA
44380