Term Information

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Accession
GO:0070054
Name
mRNA splicing, via endonucleolytic cleavage and ligation
Ontology
biological_process
Synonyms
cytosolic mRNA splicing
Alternate IDs
GO:0061012
Definition
Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons. Source: GOC:krc, GOC:mah
Comment
Note that while typically associated with tRNA splicing, splicing via endonucleolytic cleavages and subsequent ligation of the free exon ends is known to be used for some non-tRNA substrates, e.g. HAC1 (YFL031W) in S. cerevisiae and an intron in the 23S rRNA of the Archaeal species Desulfurococcus mobilis.
History
See term history for GO:0070054 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of mRNA splicing, via endonucleolytic cleavage and ligation (GO:0070054)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
mRNA splicing, via endonucleolytic cleavage and ligation [is_a relation] is_a  mRNA processing (GO:0006397)
mRNA splicing, via endonucleolytic cleavage and ligation [is_a relation] is_a  RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)

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