AmiGO 2: Term Details for "pyroptotic inflammatory response" (GO:0070269)

Accession: GO:0070269
Name: pyroptotic inflammatory response
Ontology: biological_process
Synonyms: pyroptosis
Alternate IDs: None
Definition: A gasdermin-dependent inflammatory response that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18. Gasdermins are activated by caspase-1 or caspase-4/11, or by certain granzymes. In some, but not all cells, it can lead to pyroptotic programmed cell death. Source: PMID:21760595, PMID:18846107, PMID:33883744
Comment: None
History: See term history for GO:0070269 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to pyroptotic inflammatory response (excluding "regulates").; Link to all direct and indirect annotations to pyroptotic inflammatory response (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for pyroptotic inflammatory response (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
pyroptotic inflammatory response	RO:0002162	Vertebrata (NCBITaxon:7742)
pyroptotic inflammatory response	is_a	inflammatory response (GO:0006954)

subject	relation	object
pyroptotic cell death (GO:0141201)	is_a	pyroptotic inflammatory response
negative regulation of pyroptotic inflammatory response (GO:0160028)	RO:0002212	pyroptotic inflammatory response
positive regulation of pyroptotic inflammatory response (GO:0140639)	RO:0002213	pyroptotic inflammatory response