AmiGO 2: Term Details for "elongin complex" (GO:0070449)

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Term Information

Accession: GO:0070449
Name: elongin complex
Ontology: cellular_component
Synonyms: elongin (SIII) complex, transcription elongation factor SIII complex, transcription factor B (SIII) complex
Alternate IDs: None
Definition: A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (about 100 kDa) and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa) subunits. Source: PMID:12676794
Comment: See also the cellular component terms 'cyclin-dependent protein kinase activating kinase holoenzyme complex ; GO:0019907' and 'DNA-directed RNA polymerase II, holoenzyme ; GO:0016591'.
History: See term history for GO:0070449 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to elongin complex (excluding "regulates").; Link to all direct and indirect annotations to elongin complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for elongin complex (excluding "regulates").

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UBERON:0000061 anatomical structure
CARO:0030000 biological entity
CARO:0000000 anatomical entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
UBERON:0001062 anatomical entity
GO:0005622 intracellular anatomical structure
CARO:0000006 material anatomical entity
GO:0031974 membrane-enclosed lumen
GO:0043226 organelle
CARO:0000003 connected anatomical structure
GO:0043229 intracellular organelle
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0043233 organelle lumen
GO:0005575 cellular_component
GO:0043231 intracellular membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0005634 nucleus
PR:000050567 protein-containing material entity
GO:0031981 nuclear lumen
GO:0032991 protein-containing complex
GO:0140513 nuclear protein-containing complex
GO:0005654 nucleoplasm
GO:0008023 transcription elongation factor complex
GO:0070449 elongin complex

Parents of elongin complex (GO:0070449)

subject	relation	object
elongin complex	is_a	transcription elongation factor complex (GO:0008023)

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