Term Information

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Accession
GO:0070478
Name
nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
Ontology
biological_process
Synonyms
3'-5' NMD, 3'-5' nonsense-mediated decay, 3'-5' nonsense-mediated mRNA decay, nuclear-transcribed mRNA breakdown, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA catabolism, 3'-5' exonucleolytic nonsense-mediated decay, nuclear-transcribed mRNA degradation, 3'-5' exonucleolytic nonsense-mediated decay
Alternate IDs
None
Definition
The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. Source: PMID:12769863
Comment
None
History
See term history for GO:0070478 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0070478 from QuickGO

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Parents of nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478)
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nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay [is_a relation] is_a  nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)
Children of nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nonsense-mediated decay complex (GO:0170010) [RO:0002216 relation] RO:0002216  nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
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