AmiGO 2: Term Details for "death domain binding" (GO:0070513)

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Term Information

Accession: GO:0070513
Name: death domain binding
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Binding to a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB. Source: GOC:BHF, Pfam:PF00531, InterPro:IPR000488, GOC:rl
Comment: For binding to the death effector domain, consider instead the term 'death effector domain binding ; GO:0035877'.
History: See term history for GO:0070513 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to death domain binding (excluding "regulates").; Link to all direct and indirect annotations to death domain binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for death domain binding (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0005488 binding
GO:0005515 protein binding
GO:0019904 protein domain specific binding
GO:0070513 death domain binding
GO:0051434 BH3 domain binding

Parents of death domain binding (GO:0070513)

subject	relation	object
death domain binding	is_a	protein domain specific binding (GO:0019904)

Children of death domain binding (GO:0070513)

subject	relation	object
BH3 domain binding (GO:0051434)	is_a	death domain binding

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