AmiGO 2: Term Details for "siRNA-mediated gene silencing by inhibition of translation" (GO:0070549)

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Term Information

Accession: GO:0070549
Name: siRNA-mediated gene silencing by inhibition of translation
Ontology: biological_process
Synonyms: RNA interference, negative regulation of translation, down regulation of translation involved in RNA interference, down-regulation of translation involved in RNA interference, downregulation of translation involved in RNA interference, inhibition of translation involved in RNA interference, negative regulation of translation involved in RNA interference
Alternate IDs: None
Definition: An siRNA-mediated post-transcriptional gene silencing pathway that blocks the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), an siRNA will typically mediate repression of translation if the siRNA perfectly complements elements located in the 3' untranslated region of target mRNAs. Source: GOC:mah, PMID:18771919
Comment: None
History: See term history for GO:0070549 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to siRNA-mediated gene silencing by inhibition of translation (excluding "regulates").; Link to all direct and indirect annotations to siRNA-mediated gene silencing by inhibition of translation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for siRNA-mediated gene silencing by inhibition of translation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0065007 biological regulation
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0008152 metabolic process
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0009059 macromolecule biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0009890 negative regulation of biosynthetic process
GO:0031324 negative regulation of cellular metabolic process
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0044238 primary metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0010467 gene expression
GO:0031327 negative regulation of cellular biosynthetic process
GO:0010629 negative regulation of gene expression
GO:0010605 negative regulation of macromolecule metabolic process
GO:1901576 organic substance biosynthetic process
GO:1901564 organonitrogen compound metabolic process
GO:0010608 post-transcriptional regulation of gene expression
GO:0019538 protein metabolic process
GO:0010468 regulation of gene expression
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0051172 negative regulation of nitrogen compound metabolic process
GO:1901566 organonitrogen compound biosynthetic process
GO:0016441 post-transcriptional gene silencing
GO:0051246 regulation of protein metabolic process
GO:0031047 regulatory ncRNA-mediated gene silencing
GO:0006412 translation
GO:0051248 negative regulation of protein metabolic process
GO:0006417 regulation of translation
GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing
GO:0017148 negative regulation of translation
GO:0140766 siRNA-mediated post-transcriptional gene silencing
GO:0070549 siRNA-mediated gene silencing by inhibition of translation

Parents of siRNA-mediated gene silencing by inhibition of translation (GO:0070549)

subject	relation	object
siRNA-mediated gene silencing by inhibition of translation	is_a	siRNA-mediated post-transcriptional gene silencing (GO:0140766)
siRNA-mediated gene silencing by inhibition of translation	is_a	negative regulation of translation (GO:0017148)

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