AmiGO 2: Term Details for "Shc-Grb2-Sos complex" (GO:0070619)

Accession: GO:0070619
Name: Shc-Grb2-Sos complex
Ontology: cellular_component
Synonyms: Shc-Grb2-mSos1 complex, EGF stimulated
Alternate IDs: None
Definition: A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. Source: PMID:8940013, PMID:7970708, GOC:mah
Comment: None
History: See term history for GO:0070619 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Shc-Grb2-Sos complex (excluding "regulates").; Link to all direct and indirect annotations to Shc-Grb2-Sos complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Shc-Grb2-Sos complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
Shc-Grb2-Sos complex	is_a	plasma membrane protein complex (GO:0098797)

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