AmiGO 2: Term Details for "EGFR-Grb2-Sos complex" (GO:0070620)

Accession: GO:0070620
Name: EGFR-Grb2-Sos complex
Ontology: cellular_component
Synonyms: Egfr-Grb2-mSos1 complex, EGF stimulated
Alternate IDs: None
Definition: A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. Source: PMID:8940013, PMID:7798267, GOC:mah
Comment: None
History: See term history for GO:0070620 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to EGFR-Grb2-Sos complex (excluding "regulates").; Link to all direct and indirect annotations to EGFR-Grb2-Sos complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for EGFR-Grb2-Sos complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
EGFR-Grb2-Sos complex	is_a	plasma membrane protein complex (GO:0098797)

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