AmiGO 2: Term Details for "EGFR-Shc-Grb2-Sos complex" (GO:0070621)

Accession: GO:0070621
Name: EGFR-Shc-Grb2-Sos complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway. Source: PMID:8940013, PMID:7798267, GOC:mah
Comment: None
History: See term history for GO:0070621 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to EGFR-Shc-Grb2-Sos complex (excluding "regulates").; Link to all direct and indirect annotations to EGFR-Shc-Grb2-Sos complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for EGFR-Shc-Grb2-Sos complex (excluding "regulates").