AmiGO 2: Term Details for "Sin3-type complex" (GO:0070822)

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Term Information

Accession: GO:0070822
Name: Sin3-type complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex. Source: PMID:15565322, PMID:18292778
Comment: None
History: See term history for GO:0070822 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Sin3-type complex (excluding "regulates").; Link to all direct and indirect annotations to Sin3-type complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Sin3-type complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0009987 cellular process
GO:0071840 cellular component organization or biogenesis
CARO:0030000 biological entity
GO:0016043 cellular component organization
CARO:0000000 anatomical entity
UBERON:0000061 anatomical structure
GO:0043933 protein-containing complex organization
UBERON:0001062 anatomical entity
GO:0003824 catalytic activity
CL:0000000 cell
GO:0110165 cellular anatomical entity
CARO:0000006 material anatomical entity
GO:0043226 organelle
GO:0071824 protein-DNA complex organization
GO:0006325 chromatin organization
CARO:0000003 connected anatomical structure
GO:0016787 hydrolase activity
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
GO:0140096 catalytic activity, acting on a protein
GO:0005575 cellular_component
GO:0006338 chromatin remodeling
GO:0019213 deacetylase activity
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0043231 intracellular membrane-bounded organelle
GO:0003674 molecular_function
GO:0043228 non-membrane-bounded organelle
GO:0043233 organelle lumen
PR:000050567 protein-containing material entity
GO:0140993 histone modifying activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0043232 intracellular non-membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0031981 nuclear lumen
GO:0005634 nucleus
GO:0033558 protein lysine deacetylase activity
GO:0032991 protein-containing complex
GO:1902494 catalytic complex
GO:0005694 chromosome
GO:0004407 histone deacetylase activity
GO:0140513 nuclear protein-containing complex
GO:0005654 nucleoplasm
GO:0032993 protein-DNA complex
GO:0000785 chromatin
GO:0000118 histone deacetylase complex
GO:0000228 nuclear chromosome
GO:0070822 Sin3-type complex
GO:0033698 Rpd3L complex
GO:0032221 Rpd3S complex

Parents of Sin3-type complex (GO:0070822)

subject	relation	object
Sin3-type complex	BFO:0000050	nuclear chromosome (GO:0000228)
Sin3-type complex	BFO:0000050	chromatin (GO:0000785)
Sin3-type complex	is_a	histone deacetylase complex (GO:0000118)

Children of Sin3-type complex (GO:0070822)

subject	relation	object
Rpd3S complex (GO:0032221)	is_a	Sin3-type complex
Rpd3L complex (GO:0033698)	is_a	Sin3-type complex

Sin3-type complex