AmiGO 2: Term Details for "RISC complex assembly" (GO:0070922)

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Term Information

Accession: GO:0070922
Name: RISC complex assembly
Ontology: biological_process
Synonyms: RISC assembly, gene silencing by RNA, small RNA loading onto RISC, small RNA loading onto RISC, miRNA loading onto RISC, siRNA loading onto RISC involved in RNA interference, siRNA loading onto RISC involved in gene silencing by small RNA, miRISC assembly
Alternate IDs: GO:0035280, GO:0070923, GO:0035087
Definition: The process in which a single-stranded small RNA is incorporated within the RNA-initiated silencing complex (RISC). The assembly includes the maturation of the small RNA, the stabilization of the complex by accessory proteins of the RISC complex, duplex separation and the release of the second strand, forming a base-pairing completent complex that mediates gene silencing by small RNA. Source: PMID:27184117, PMID:14512631, PMID:14744438, PMID:22233755, PMID:19239886
Comment: None
History: See term history for GO:0070922 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RISC complex assembly (excluding "regulates").; Link to all direct and indirect annotations to RISC complex assembly (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RISC complex assembly (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0050789 regulation of biological process
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0008152 metabolic process
GO:0048519 negative regulation of biological process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
GO:0044249 cellular biosynthetic process
GO:0043170 macromolecule metabolic process
GO:0048523 negative regulation of cellular process
GO:0009892 negative regulation of metabolic process
GO:0071704 organic substance metabolic process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0071840 cellular component organization or biogenesis
GO:0009059 macromolecule biosynthetic process
GO:0009890 negative regulation of biosynthetic process
GO:0031324 negative regulation of cellular metabolic process
GO:1901576 organic substance biosynthetic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0044085 cellular component biogenesis
GO:0016043 cellular component organization
GO:0010467 gene expression
GO:0031327 negative regulation of cellular biosynthetic process
GO:0010605 negative regulation of macromolecule metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0022607 cellular component assembly
GO:0010558 negative regulation of macromolecule biosynthetic process
GO:0043933 protein-containing complex organization
GO:0010468 regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0065003 protein-containing complex assembly
GO:0071826 protein-RNA complex organization
GO:0022613 ribonucleoprotein complex biogenesis
GO:0022618 protein-RNA complex assembly
GO:0031047 regulatory ncRNA-mediated gene silencing
GO:0070922 RISC complex assembly
GO:0070578 RISC-loading complex

Parents of RISC complex assembly (GO:0070922)

subject	relation	object
RISC complex assembly	BFO:0000050	regulatory ncRNA-mediated gene silencing (GO:0031047)
RISC complex assembly	is_a	protein-RNA complex assembly (GO:0022618)

Children of RISC complex assembly (GO:0070922)

subject	relation	object
RISC-loading complex (GO:0070578)	RO:0002216	RISC complex assembly

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