Term Information

Feedback 
Accession
GO:0071159
Name
NF-kappaB complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression. Source: ISBN:0849327946
Comment
None
History
See term history for GO:0071159 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

Loading...
pending...
View this term in QuickGO.

Graph of GO:0071159 from QuickGO

Additional external viewing options
Additional internal viewing options
Parents of NF-kappaB complex (GO:0071159)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NF-kappaB complex [is_a relation] is_a  nuclear protein-containing complex (GO:0140513)
Children of NF-kappaB complex (GO:0071159)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
NF-kappaB p50/p65 complex (GO:0035525) [is_a relation] is_a  NF-kappaB complex
GONUTS Add usage comments for this term on the GONUTS wiki.