AmiGO 2: Term Details for "cellular response to hypoxia" (GO:0071456)

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Term Information

Accession: GO:0071456
Name: cellular response to hypoxia
Ontology: biological_process
Synonyms: cellular response to hypoxic stress, cellular response to lowered oxygen tension
Alternate IDs: None
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. Source: GOC:mah
Comment: Note that this term should not be confused with 'cellular response to anoxia ; GO:0071454'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%.
History: See term history for GO:0071456 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to cellular response to hypoxia (excluding "regulates").; Link to all direct and indirect annotations to cellular response to hypoxia (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for cellular response to hypoxia (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0050896 response to stimulus
GO:0008150 biological_process
GO:0051716 cellular response to stimulus
GO:0009628 response to abiotic stimulus
GO:0042221 response to chemical
GO:0009987 cellular process
GO:0070887 cellular response to chemical stimulus
GO:0070482 response to oxygen levels
GO:0071453 cellular response to oxygen levels
GO:0036293 response to decreased oxygen levels
GO:0006950 response to stress
GO:0036294 cellular response to decreased oxygen levels
GO:0033554 cellular response to stress
GO:0001666 response to hypoxia
GO:0071456 cellular response to hypoxia
GO:0097411 hypoxia-inducible factor-1alpha signaling pathway
GO:1990144 intrinsic apoptotic signaling pathway in response to hypoxia
GO:1900038 negative regulation of cellular response to hypoxia
GO:1900039 positive regulation of cellular response to hypoxia
GO:1900037 regulation of cellular response to hypoxia

Parents of cellular response to hypoxia (GO:0071456)

subject	relation	object
cellular response to hypoxia	is_a	response to hypoxia (GO:0001666)
cellular response to hypoxia	is_a	cellular response to stress (GO:0033554)
cellular response to hypoxia	is_a	cellular response to decreased oxygen levels (GO:0036294)

Children of cellular response to hypoxia (GO:0071456)

subject	relation	object
regulation of cellular response to hypoxia (GO:1900037)	RO:0002211	cellular response to hypoxia
positive regulation of cellular response to hypoxia (GO:1900039)	RO:0002213	cellular response to hypoxia
intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144)	BFO:0000050	cellular response to hypoxia
hypoxia-inducible factor-1alpha signaling pathway (GO:0097411)	BFO:0000050	cellular response to hypoxia
negative regulation of cellular response to hypoxia (GO:1900038)	RO:0002212	cellular response to hypoxia

Reactome: R-HSA-1234174