AmiGO 2: Term Details for "ubiquitin-dependent protein catabolic process via the N-end rule pathway" (GO:0071596)

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Term Information

Accession: GO:0071596
Name: ubiquitin-dependent protein catabolic process via the N-end rule pathway
Ontology: biological_process
Synonyms: ubiquitin-dependent protein breakdown via the N-end rule pathway, ubiquitin-dependent protein catabolism via the N-end rule pathway, ubiquitin-dependent protein degradation via the N-end rule pathway
Alternate IDs: None
Definition: The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. Source: PMID:9112437, GOC:rb, GOC:mah, PMID:19246002
Comment: None
History: See term history for GO:0071596 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to ubiquitin-dependent protein catabolic process via the N-end rule pathway (excluding "regulates").; Link to all direct and indirect annotations to ubiquitin-dependent protein catabolic process via the N-end rule pathway (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ubiquitin-dependent protein catabolic process via the N-end rule pathway (excluding "regulates").

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0009056 catabolic process
GO:0071704 organic substance metabolic process
GO:0009057 macromolecule catabolic process
GO:0043170 macromolecule metabolic process
GO:1901575 organic substance catabolic process
GO:1901564 organonitrogen compound metabolic process
GO:0044238 primary metabolic process
GO:0019538 protein metabolic process
GO:0043632 modification-dependent macromolecule catabolic process
GO:1901565 organonitrogen compound catabolic process
GO:0030163 protein catabolic process
GO:0006508 proteolysis
GO:0051603 proteolysis involved in protein catabolic process
GO:0019941 modification-dependent protein catabolic process
GO:0010498 proteasomal protein catabolic process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway

Parents of ubiquitin-dependent protein catabolic process via the N-end rule pathway (GO:0071596)

subject	relation	object
ubiquitin-dependent protein catabolic process via the N-end rule pathway	is_a	proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)

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