Term Information

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Accession
GO:0071630
Name
nuclear protein quality control by the ubiquitin-proteasome system
Ontology
biological_process
Synonyms
nucleus-associated proteasomal ubiquitin-dependent protein breakdown, nucleus-associated proteasomal ubiquitin-dependent protein catabolism, nucleus-associated proteasomal ubiquitin-dependent protein degradation, ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome
Alternate IDs
None
Definition
A protein quality control pathway that results in the breakdown of misfolded, damaged or unassembled proteins via a mechanism in which the proteins are ubiquitinated, and then targeted to nuclear proteasomes for degradation. Source: PMID:21211726, PMID:20080635
Comment
None
History
See term history for GO:0071630 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0071630 from QuickGO

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Parents of nuclear protein quality control by the ubiquitin-proteasome system (GO:0071630)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
nuclear protein quality control by the ubiquitin-proteasome system [RO:0002160 relation] RO:0002160  Eukaryota (NCBITaxon:2759)
nuclear protein quality control by the ubiquitin-proteasome system [is_a relation] is_a  protein quality control for misfolded or incompletely synthesized proteins (GO:0006515)
nuclear protein quality control by the ubiquitin-proteasome system [is_a relation] is_a  proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)
nuclear protein quality control by the ubiquitin-proteasome system [BFO:0000050 relation] BFO:0000050  cellular response to misfolded protein (GO:0071218)
Children of nuclear protein quality control by the ubiquitin-proteasome system (GO:0071630)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
inner nuclear membrane-associated protein degradation pathway (GO:0180027) [is_a relation] is_a  nuclear protein quality control by the ubiquitin-proteasome system
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