AmiGO 2: Term Details for "dimeric IgA immunoglobulin complex" (GO:0071750)

Term Information

Accession: GO:0071750
Name: dimeric IgA immunoglobulin complex
Ontology: cellular_component
Synonyms: dimeric IgA antibody, dimeric IgA1 antibody
Alternate IDs: None
Definition: A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. Source: ISBN:0781765196, PMID:16362985, GOC:add
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. Dimeric IgA is by far the most common form of polymeric IgA. In human only the IgA1 isotype is capable of a dimeric form.
History: See term history for GO:0071750 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to dimeric IgA immunoglobulin complex (excluding "regulates").; Link to all direct and indirect annotations to dimeric IgA immunoglobulin complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for dimeric IgA immunoglobulin complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
CARO:0000006 material anatomical entity
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0110165 cellular anatomical entity
GO:0005575 cellular_component
PR:000050567 protein-containing material entity
GO:0005576 extracellular region
GO:0032991 protein-containing complex
GO:0005615 extracellular space
GO:0019814 immunoglobulin complex
GO:0071745 IgA immunoglobulin complex
GO:0042571 immunoglobulin complex, circulating
GO:0071746 IgA immunoglobulin complex, circulating
GO:0071749 polymeric IgA immunoglobulin complex
GO:0071750 dimeric IgA immunoglobulin complex
GO:0071752 secretory dimeric IgA immunoglobulin complex

Parents of dimeric IgA immunoglobulin complex (GO:0071750)

subject	relation	object
dimeric IgA immunoglobulin complex	is_a	polymeric IgA immunoglobulin complex (GO:0071749)

Children of dimeric IgA immunoglobulin complex (GO:0071750)

subject	relation	object
secretory dimeric IgA immunoglobulin complex (GO:0071752)	is_a	dimeric IgA immunoglobulin complex

GONUTS Add usage comments for this term on the GONUTS wiki.