AmiGO 2: Term Details for "secretory IgA immunoglobulin complex" (GO:0071751)

Accession: GO:0071751
Name: secretory IgA immunoglobulin complex
Ontology: cellular_component
Synonyms: sIgA antibody, secretory IgA antibody, sIgA1 antibody
Alternate IDs: None
Definition: A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component. Source: ISBN:0781765196, PMID:16362985, GOC:add
Comment: Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.
History: See term history for GO:0071751 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to secretory IgA immunoglobulin complex (excluding "regulates").; Link to all direct and indirect annotations to secretory IgA immunoglobulin complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for secretory IgA immunoglobulin complex (excluding "regulates").