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IgM immunoglobulin complex

Term Information

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Accession
GO:0071753
Name
IgM immunoglobulin complex
Ontology
cellular_component
Synonyms
None
Alternate IDs
None
Definition
A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. Source: ISBN:0781765196, GOC:add, PMID:20176268
Comment
Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
History
See term history for GO:0071753 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of IgM immunoglobulin complex (GO:0071753)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
IgM immunoglobulin complex [is_a relation] is_a  immunoglobulin complex (GO:0019814)
Children of IgM immunoglobulin complex (GO:0071753)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
fraction F mature B cell (CL:0002056) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
naive B cell (CL:0000788) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
Bm3-delta B cell (CL:0000963) [CL:4030046 relation] CL:4030046  IgM immunoglobulin complex
precursor B cell (CL:0000817) [CL:4030046 relation] CL:4030046  IgM immunoglobulin complex
IgM memory B cell (CL:0000971) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
marginal zone B cell of spleen (CL:0000845) [RO:0015015 relation] RO:0015015  IgM immunoglobulin complex
IgM B cell receptor complex (GO:0071755) [is_a relation] is_a  IgM immunoglobulin complex
Peyer's patch B cell (CL:0002402) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
IgM immunoglobulin complex, circulating (GO:0071754) [is_a relation] is_a  IgM immunoglobulin complex
unswitched memory B cell (CL:0000970) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
follicular B cell (CL:0000843) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
immature B cell (CL:0000816) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
transitional stage B cell (CL:0000818) [RO:0002104 relation] RO:0002104  IgM immunoglobulin complex
class switched memory B cell (CL:0000972) [CL:4030046 relation] CL:4030046  IgM immunoglobulin complex
B-1 B cell (CL:0000819) [RO:0015015 relation] RO:0015015  IgM immunoglobulin complex
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