AmiGO 2: Term Details for "IgM immunoglobulin complex, circulating" (GO:0071754)

Accession: GO:0071754
Name: IgM immunoglobulin complex, circulating
Ontology: cellular_component
Synonyms: IgM antibody
Alternate IDs: None
Definition: A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph. Source: ISBN:0781765196, GOC:add, PMID:20176268
Comment: Note that an IgM immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
History: See term history for GO:0071754 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to IgM immunoglobulin complex, circulating (excluding "regulates").; Link to all direct and indirect annotations to IgM immunoglobulin complex, circulating (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for IgM immunoglobulin complex, circulating (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
IgM immunoglobulin complex, circulating	is_a	IgM immunoglobulin complex (GO:0071753)
IgM immunoglobulin complex, circulating	is_a	immunoglobulin complex, circulating (GO:0042571)

subject	relation	object
IgM plasmablast (CL:0000983)	RO:0003000	IgM immunoglobulin complex, circulating
pentameric IgM immunoglobulin complex (GO:0071756)	is_a	IgM immunoglobulin complex, circulating
IgM plasma cell (CL:0000986)	RO:0003000	IgM immunoglobulin complex, circulating
IgM short lived plasma cell (CL:0000978)	RO:0003000	IgM immunoglobulin complex, circulating
hexameric IgM immunoglobulin complex (GO:0071757)	is_a	IgM immunoglobulin complex, circulating

IgM immunoglobulin complex, circulating