AmiGO 2: Term Details for "LUBAC complex" (GO:0071797)

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Term Information

Accession: GO:0071797
Name: LUBAC complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex. Source: PMID:17006537, GOC:sp, PMID:19136968, PMID:21455180
Comment: None
History: See term history for GO:0071797 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to LUBAC complex (excluding "regulates").; Link to all direct and indirect annotations to LUBAC complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for LUBAC complex (excluding "regulates").

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GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0003824 catalytic activity
GO:0016755 aminoacyltransferase activity
GO:0140096 catalytic activity, acting on a protein
GO:0003674 molecular_function
GO:0005575 cellular_component
GO:0032991 protein-containing complex
PR:000050567 protein-containing material entity
GO:0019787 ubiquitin-like protein transferase activity
GO:1902494 catalytic complex
GO:0061659 ubiquitin-like protein ligase activity
GO:0004842 ubiquitin-protein transferase activity
GO:0140535 intracellular protein-containing complex
GO:1990234 transferase complex
GO:0061630 ubiquitin protein ligase activity
GO:0000151 ubiquitin ligase complex
GO:0071797 LUBAC complex

Parents of LUBAC complex (GO:0071797)

subject	relation	object
LUBAC complex	is_a	ubiquitin ligase complex (GO:0000151)

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