AmiGO 2: Term Details for "NLRP1 inflammasome complex" (GO:0072558)

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Term Information

Accession: GO:0072558
Name: NLRP1 inflammasome complex
Ontology: cellular_component
Synonyms: NALP1 inflammasome complex
Alternate IDs: None
Definition: An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential. Source: PMID:20303873, GOC:BHF, GOC:add, GOC:vp
Comment: None
History: See term history for GO:0072558 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to NLRP1 inflammasome complex (excluding "regulates").; Link to all direct and indirect annotations to NLRP1 inflammasome complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for NLRP1 inflammasome complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
GO:0008150 biological_process
CARO:0000000 anatomical entity
GO:0065007 biological regulation
UBERON:0001062 anatomical entity
UBERON:0000061 anatomical structure
CARO:0000006 material anatomical entity
GO:0050789 regulation of biological process
GO:0048583 regulation of response to stimulus
GO:0050896 response to stimulus
GO:0006950 response to stress
CL:0000000 cell
GO:0110165 cellular anatomical entity
CARO:0000003 connected anatomical structure
GO:0006952 defense response
UBERON:0000465 material anatomical entity
GO:0048518 positive regulation of biological process
GO:0080134 regulation of response to stress
GO:0009605 response to external stimulus
GO:0005575 cellular_component
GO:0006954 inflammatory response
GO:0005622 intracellular anatomical structure
GO:0048584 positive regulation of response to stimulus
GO:0031347 regulation of defense response
GO:0032101 regulation of response to external stimulus
GO:0005737 cytoplasm
GO:0031349 positive regulation of defense response
GO:0032103 positive regulation of response to external stimulus
PR:000050567 protein-containing material entity
GO:0050727 regulation of inflammatory response
GO:0005829 cytosol
GO:0050729 positive regulation of inflammatory response
GO:0032991 protein-containing complex
GO:0061702 canonical inflammasome complex
GO:0072558 NLRP1 inflammasome complex

Parents of NLRP1 inflammasome complex (GO:0072558)

subject	relation	object
NLRP1 inflammasome complex	is_a	canonical inflammasome complex (GO:0061702)

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