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DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity

Term Information

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Accession
GO:0072586
Name
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2. Source: GOC:mah
Comment
None
History
See term history for GO:0072586 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity (GO:0072586)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity [RO:0002578 relation] RO:0002578  DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity (GO:0003918)
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity [is_a relation] is_a  enzyme regulator activity (GO:0030234)
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity [is_a relation] is_a  ATPase regulator activity (GO:0060590)
Children of DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity (GO:0072586)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity (GO:0072587) [is_a relation] is_a  DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity (GO:0008657) [is_a relation] is_a  DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
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