AmiGO 2: Term Details for "S-nitrosoglutathione reductase (NADH) activity" (GO:0080007)

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Term Information

Accession: GO:0080007
Name: S-nitrosoglutathione reductase (NADH) activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the reaction: S-nitrosoglutathione + NADH + H+ = S-(hydroxysulfenamide)glutathione + NAD+. Source: PMID:27094420, PMID:30795534, PMID:11260719
Comment: S-(hydroxysulfenamide)glutathione (GSNHOH) is an unstable intermediate. At high GSH levels, it is decomposed to glutathione disulfide (GSSG) and hydroxylamine. At low GSH levels, GSNHOH spontaneously converts to glutathione sulfinamid (GSONH2), which can be hydrolyzed to glutathione sulfinic acid (GSOOH) and ammonia.
History: See term history for GO:0080007 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to S-nitrosoglutathione reductase (NADH) activity (excluding "regulates").; Link to all direct and indirect annotations to S-nitrosoglutathione reductase (NADH) activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for S-nitrosoglutathione reductase (NADH) activity (excluding "regulates").

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0080007 S-nitrosoglutathione reductase (NADH) activity

Parents of S-nitrosoglutathione reductase (NADH) activity (GO:0080007)

subject	relation	object
S-nitrosoglutathione reductase (NADH) activity	is_a	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

This term has no children.

MetaCyc: RXN-17884