AmiGO 2: Term Details for "negative regulation of release of cytochrome c from mitochondria" (GO:0090201)

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Term Information

Accession: GO:0090201
Name: negative regulation of release of cytochrome c from mitochondria
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation. Source: GOC:dph, GOC:tb, GOC:BHF, GOC:mtg_apoptosis
Comment: The release of cytochrome c from mitochondria is a central event in the signaling phase of the apoptotic process, and it is often used by researchers to monitor this type of cell death. Any event that induces apoptosis will at some point induce the release of cytochrome c from mitochondria. Therefore, this term should only be used to annotate gene products that directly and negatively regulate this process.
History: See term history for GO:0090201 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to negative regulation of release of cytochrome c from mitochondria (excluding "regulates").; Link to all direct and indirect annotations to negative regulation of release of cytochrome c from mitochondria (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for negative regulation of release of cytochrome c from mitochondria (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0065007 biological regulation
GO:0009987 cellular process
GO:0007154 cell communication
GO:0008219 cell death
GO:0012501 programmed cell death
GO:0050789 regulation of biological process
GO:0050794 regulation of cellular process
GO:0050896 response to stimulus
GO:0023052 signaling
GO:0006915 apoptotic process
GO:0016043 cellular component organization
GO:0071840 cellular component organization or biogenesis
GO:0051716 cellular response to stimulus
GO:0048519 negative regulation of biological process
GO:0048523 negative regulation of cellular process
GO:0006996 organelle organization
GO:0010646 regulation of cell communication
GO:0043067 regulation of programmed cell death
GO:0048583 regulation of response to stimulus
GO:0023051 regulation of signaling
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:0007005 mitochondrion organization
GO:0010648 negative regulation of cell communication
GO:0043069 negative regulation of programmed cell death
GO:0048585 negative regulation of response to stimulus
GO:0023057 negative regulation of signaling
GO:0042981 regulation of apoptotic process
GO:0051128 regulation of cellular component organization
GO:0033043 regulation of organelle organization
GO:0009966 regulation of signal transduction
GO:0008637 apoptotic mitochondrial changes
GO:0043066 negative regulation of apoptotic process
GO:0051129 negative regulation of cellular component organization
GO:0009968 negative regulation of signal transduction
GO:2001233 regulation of apoptotic signaling pathway
GO:0010821 regulation of mitochondrion organization
GO:0001836 release of cytochrome c from mitochondria
GO:2001234 negative regulation of apoptotic signaling pathway
GO:0010639 negative regulation of organelle organization
GO:0090199 regulation of release of cytochrome c from mitochondria
GO:0090201 negative regulation of release of cytochrome c from mitochondria

Parents of negative regulation of release of cytochrome c from mitochondria (GO:0090201)

subject	relation	object
negative regulation of release of cytochrome c from mitochondria	RO:0002212	release of cytochrome c from mitochondria (GO:0001836)
negative regulation of release of cytochrome c from mitochondria	is_a	negative regulation of organelle organization (GO:0010639)
negative regulation of release of cytochrome c from mitochondria	is_a	negative regulation of apoptotic signaling pathway (GO:2001234)
negative regulation of release of cytochrome c from mitochondria	is_a	regulation of release of cytochrome c from mitochondria (GO:0090199)

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