Term Information

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Accession
GO:0090489
Name
tryptophan N-monooxygenase activity
Ontology
molecular_function
Synonyms
L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating), tryptophan N-hydroxylase activity
Alternate IDs
None
Definition
Catalyzes the multi-step reaction: L-tryptophan + 2 O2 + 2 reduced [NADPH--hemoprotein reductase] = (E)-(indol-3-yl)acetaldehyde oxime + CO2 + 2 H+ + 3 H2O + 2 oxidized [NADPH--hemoprotein reductase]. Source: RHEA:33279
Comment
None
History
See term history for GO:0090489 at QuickGO
Chem. react.
has participant hydron
has participant water
has participant dioxygen
has participant carbon dioxide
has participant (E)-indol-3-ylacetaldehyde oxime
has participant FMNH2(2-)
has participant FMN(3-)
has participant L-tryptophan zwitterion
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of tryptophan N-monooxygenase activity (GO:0090489)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  dioxygen (CHEBI:15379)
tryptophan N-monooxygenase activity [is_a relation] is_a  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen (GO:0016712)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  carbon dioxide (CHEBI:16526)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  (E)-indol-3-ylacetaldehyde oxime (CHEBI:17545)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  FMNH2(2-) (CHEBI:57618)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  FMN(3-) (CHEBI:58210)
tryptophan N-monooxygenase activity [RO:0000057 relation] RO:0000057  L-tryptophan zwitterion (CHEBI:57912)

This term has no children.

EC
1.14.14.156
KEGG_REACTION
R08160
RHEA
33279