AmiGO 2: Term Details for "endocardial cushion to mesenchymal transition" (GO:0090500)

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Term Information

Accession: GO:0090500
Name: endocardial cushion to mesenchymal transition
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. Source: GOC:dph, GOC:tb
Comment: None
History: See term history for GO:0090500 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to endocardial cushion to mesenchymal transition (excluding "regulates").; Link to all direct and indirect annotations to endocardial cushion to mesenchymal transition (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for endocardial cushion to mesenchymal transition (excluding "regulates").

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For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0048856 anatomical structure development
GO:0032501 multicellular organismal process
GO:0009987 cellular process
GO:0032502 developmental process
GO:0007275 multicellular organism development
GO:0048513 animal organ development
GO:0048869 cellular developmental process
GO:0048731 system development
GO:0009888 tissue development
GO:0009653 anatomical structure morphogenesis
GO:0030154 cell differentiation
GO:0072359 circulatory system development
GO:0060485 mesenchyme development
GO:0009887 animal organ morphogenesis
GO:0007507 heart development
GO:0048762 mesenchymal cell differentiation
GO:0001837 epithelial to mesenchymal transition
GO:0003007 heart morphogenesis
GO:0060317 cardiac epithelial to mesenchymal transition
GO:0090500 endocardial cushion to mesenchymal transition
GO:0003202 endocardial cushion to mesenchymal transition involved in cardiac skeleton development
GO:0003200 endocardial cushion to mesenchymal transition involved in heart chamber septation
GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation
GO:0140050 negative regulation of endocardial cushion to mesenchymal transition
GO:0140051 positive regulation of endocardial cushion to mesenchymal transition
GO:0140049 regulation of endocardial cushion to mesenchymal transition

Parents of endocardial cushion to mesenchymal transition (GO:0090500)

subject	relation	object
endocardial cushion to mesenchymal transition	is_a	cardiac epithelial to mesenchymal transition (GO:0060317)

Children of endocardial cushion to mesenchymal transition (GO:0090500)

subject	relation	object
endocardial cushion to mesenchymal transition involved in cardiac skeleton development (GO:0003202)	is_a	endocardial cushion to mesenchymal transition
endocardial cushion to mesenchymal transition involved in heart chamber septation (GO:0003200)	is_a	endocardial cushion to mesenchymal transition
negative regulation of endocardial cushion to mesenchymal transition (GO:0140050)	RO:0002212	endocardial cushion to mesenchymal transition
endocardial cushion to mesenchymal transition involved in heart valve formation (GO:0003199)	is_a	endocardial cushion to mesenchymal transition
positive regulation of endocardial cushion to mesenchymal transition (GO:0140051)	RO:0002213	endocardial cushion to mesenchymal transition
regulation of endocardial cushion to mesenchymal transition (GO:0140049)	RO:0002211	endocardial cushion to mesenchymal transition

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