AmiGO 2: Term Details for "mature conventional dendritic cell differentiation" (GO:0097029)

Accession: GO:0097029
Name: mature conventional dendritic cell differentiation
Ontology: biological_process
Synonyms: None
Alternate IDs: None
Definition: The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells. Source: PMID:15845453, http://www.rndsystems.com/mini_review_detail_objectname_MR02_DendriticCellMat.aspx, GOC:BHF
Comment: Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'.
History: See term history for GO:0097029 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to mature conventional dendritic cell differentiation (excluding "regulates").; Link to all direct and indirect annotations to mature conventional dendritic cell differentiation (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for mature conventional dendritic cell differentiation (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
mature conventional dendritic cell differentiation	is_a	myeloid leukocyte differentiation (GO:0002573)
mature conventional dendritic cell differentiation	RO:0002315	mature conventional dendritic cell (CL:0000841)
mature conventional dendritic cell differentiation	is_a	dendritic cell differentiation (GO:0097028)

This term has no children.

GONUTS Add usage comments for this term on the GONUTS wiki.