AmiGO 2: Term Details for "DH domain binding" (GO:0097161)

Accession: GO:0097161
Name: DH domain binding
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Binding to a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket. Source: InterPro:IPR000219, GOC:yaf, PMID:12775584
Comment: None
History: See term history for GO:0097161 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to DH domain binding (excluding "regulates").; Link to all direct and indirect annotations to DH domain binding (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for DH domain binding (excluding "regulates").