AmiGO 2: Term Details for "R2TP complex" (GO:0097255)

Accession: GO:0097255
Name: R2TP complex
Ontology: cellular_component
Synonyms: None
Alternate IDs: None
Definition: A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others. Source: GOC:mcc, PMID:15766533, PMID:21925213
Comment: None
History: See term history for GO:0097255 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to R2TP complex (excluding "regulates").; Link to all direct and indirect annotations to R2TP complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for R2TP complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
R2TP complex	is_a	protein-containing complex (GO:0032991)

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