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Accession
GO:0097256
Name
phenyllactate dehydrogenase activity
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the reaction: (R)-3-phenyllactate + NAD+ = 3-phenylpyruvate + H+ + NADH. Source: PMID:10849007, GOC:pde, RHEA:38351
Comment
This enzymatic activity is usually negligible, but may become prominent when phenylalanine levels are abnormally high as in the human disease phenylketonuria (PKU).
History
See term history for GO:0097256 at QuickGO
Chem. react.
has participant NAD(1-)
has participant keto-phenylpyruvate
has participant hydron
has participant NADH(2-)
has participant (R)-3-phenyllactate
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0097256 from QuickGO

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Parents of phenyllactate dehydrogenase activity (GO:0097256)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
phenyllactate dehydrogenase activity [is_a relation] is_a  oxidoreductase activity, acting on CH-OH group of donors (GO:0016614)
phenyllactate dehydrogenase activity [RO:0000057 relation] RO:0000057  NAD(1-) (CHEBI:57540)
phenyllactate dehydrogenase activity [RO:0000057 relation] RO:0000057  keto-phenylpyruvate (CHEBI:18005)
phenyllactate dehydrogenase activity [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
phenyllactate dehydrogenase activity [RO:0000057 relation] RO:0000057  NADH(2-) (CHEBI:57945)
phenyllactate dehydrogenase activity [RO:0000057 relation] RO:0000057  (R)-3-phenyllactate (CHEBI:11009)

This term has no children.

EC
1.1.1.110
RHEA
38351