AmiGO 2: Term Details for "activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" (GO:0097296)

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Term Information

Accession: GO:0097296
Name: activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
Ontology: biological_process
Synonyms: activation of cysteine-type endopeptidase activity involved in apoptotic signalling pathway, activation of initiator caspase activity
Alternate IDs: None
Definition: Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway. Source: GOC:mtg_apoptosis
Comment: Components of the DISC (death-inducing signaling complex) may be annotated to this term. These include ligand-bound receptors such as FAS/CD95 (though care should be taken because FAS can also act as a non-apoptotic signal transducer), and signaling molecules such as FADD (FAS-associated protein with a death domain), cIAPs (cellular inhibitor of apoptosis proteins), c-FLIPs and caspases 8 and 10. Note that GO:0097296 should only be used to annotate gene products directly involved in the initiation or start up of an inactive cysteine-type endopeptidase activity involved in the apoptotic signaling pathway (also known as an initiator caspase). If the evidence provided is not sufficient to account for direct activation of this enzymatic activity, consider using the more generic terms GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway or GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process.
History: See term history for GO:0097296 at QuickGO
Chem. react.: None
Subset: gocheck_do_not_annotate
Related: Link to all genes and gene products annotated to activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (excluding "regulates").; Link to all direct and indirect annotations to activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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GO:0008150 biological_process
GO:0008152 metabolic process
GO:0050789 regulation of biological process
GO:0065007 biological regulation
GO:0043170 macromolecule metabolic process
GO:0003674 molecular_function
GO:0006807 nitrogen compound metabolic process
GO:0071704 organic substance metabolic process
GO:0048518 positive regulation of biological process
GO:0044238 primary metabolic process
GO:0019222 regulation of metabolic process
GO:0003824 catalytic activity
GO:1901564 organonitrogen compound metabolic process
GO:0009893 positive regulation of metabolic process
GO:0019538 protein metabolic process
GO:0060255 regulation of macromolecule metabolic process
GO:0065009 regulation of molecular function
GO:0051171 regulation of nitrogen compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0016787 hydrolase activity
GO:0010604 positive regulation of macromolecule metabolic process
GO:0044093 positive regulation of molecular function
GO:0051173 positive regulation of nitrogen compound metabolic process
GO:0006508 proteolysis
GO:0050790 regulation of catalytic activity
GO:0051246 regulation of protein metabolic process
GO:0140096 catalytic activity, acting on a protein
GO:0009987 cellular process
GO:0008233 peptidase activity
GO:0043085 positive regulation of catalytic activity
GO:0051247 positive regulation of protein metabolic process
GO:0051336 regulation of hydrolase activity
GO:0030162 regulation of proteolysis
GO:0008219 cell death
GO:0004175 endopeptidase activity
GO:0051345 positive regulation of hydrolase activity
GO:0045862 positive regulation of proteolysis
GO:0052547 regulation of peptidase activity
GO:0050896 response to stimulus
GO:0007154 cell communication
GO:0051716 cellular response to stimulus
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0010952 positive regulation of peptidase activity
GO:0012501 programmed cell death
GO:0050794 regulation of cellular process
GO:0052548 regulation of endopeptidase activity
GO:0023052 signaling
GO:0006915 apoptotic process
GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process
GO:0010950 positive regulation of endopeptidase activity
GO:2000116 regulation of cysteine-type endopeptidase activity
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:2001056 positive regulation of cysteine-type endopeptidase activity
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Parents of activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:0097296)

subject	relation	object
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	is_a	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway (GO:2001269)

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