AmiGO 2: Term Details for "Gemini of coiled bodies" (GO:0097504)

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Term Information

Accession: GO:0097504
Name: Gemini of coiled bodies
Ontology: cellular_component
Synonyms: Gems
Alternate IDs: None
Definition: Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA). Source: PMID:11031238, PMID:9683623, GOC:pr, Wikipedia:Cell_nucleus#Cajal_bodies_and_gems
Comment: None
History: See term history for GO:0097504 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to Gemini of coiled bodies (excluding "regulates").; Link to all direct and indirect annotations to Gemini of coiled bodies (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for Gemini of coiled bodies (excluding "regulates").

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UBERON:0000061 anatomical structure
CARO:0030000 biological entity
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0043226 organelle
CARO:0000000 anatomical entity
GO:0005622 intracellular anatomical structure
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0031974 membrane-enclosed lumen
UBERON:0001062 anatomical entity
GO:0043231 intracellular membrane-bounded organelle
CARO:0000006 material anatomical entity
GO:0043233 organelle lumen
CARO:0000003 connected anatomical structure
GO:0070013 intracellular organelle lumen
UBERON:0000465 material anatomical entity
GO:0005634 nucleus
GO:0005575 cellular_component
GO:0031981 nuclear lumen
GO:0005654 nucleoplasm
GO:0016604 nuclear body
GO:0097504 Gemini of coiled bodies

Parents of Gemini of coiled bodies (GO:0097504)

subject	relation	object
Gemini of coiled bodies	is_a	nuclear body (GO:0016604)

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