Term Information

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Accession
GO:0097546
Name
ciliary base
Ontology
cellular_component
Synonyms
cilial base, cilium base, flagellar base, flagellum base
Alternate IDs
None
Definition
Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area. Source: GOC:krc, GOC:cilia, PMID:22653444
Comment
Due to resolution issues, researchers are often unable to assign protein localization to more specific ciliary compartments such as the basal body, transition fibers or transition zone, and instead refer to 'ciliary base'. The terms GO:0036064 'ciliary basal body', GO:0097539 'ciliary transition fiber' and GO:0035869 'ciliary transition zone' represent strictly defined compartments at the ciliary base and should be used for annotation whenever possible. Also, note that cilia and eukaryotic flagella are deemed to be equivalent.
History
See term history for GO:0097546 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of ciliary base (GO:0097546)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
ciliary base [is_a relation] is_a  protein-containing material entity (PR:000050567)
ciliary base [BFO:0000050 relation] BFO:0000050  cilium (GO:0005929)
ciliary base [is_a relation] is_a  cellular anatomical entity (GO:0110165)
ciliary base [BFO:0000051 relation] BFO:0000051  ciliary transition fiber (GO:0097539)
ciliary base [BFO:0000051 relation] BFO:0000051  ciliary transition zone (GO:0035869)
ciliary base [RO:0002162 relation] RO:0002162  Eukaryota (NCBITaxon:2759)

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