double-strand break repair via classical nonhomologous end joining
Ontology
biological_process
Synonyms
canonical nonhomologous end joining, C-NHEJ
Alternate IDs
None
Definition
An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).
Source:
GOC:rph,
PMID:18584027
Link
to all genes and gene products annotated to double-strand break repair via classical nonhomologous end joining (excluding "regulates").
Link
to all direct and indirect annotations
to double-strand break repair via classical nonhomologous end joining (excluding "regulates").
Link
to all direct and indirect annotations download (limited to first 10,000)
for double-strand break repair via classical nonhomologous end joining (excluding "regulates").