AmiGO 2: Term Details for "double-strand break repair via alternative nonhomologous end joining" (GO:0097681)

Accession: GO:0097681
Name: double-strand break repair via alternative nonhomologous end joining
Ontology: biological_process
Synonyms: double-strand break repair via microhomology-mediated end joining, A-NHEJ, MMEJ, alt-NHEJ
Alternate IDs: None
Definition: An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment. Source: GOC:rph, PMID:18584027, PMID:21655080, Wikipedia:Microhomology-mediated_end_joining
Comment: None
History: See term history for GO:0097681 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to double-strand break repair via alternative nonhomologous end joining (excluding "regulates").; Link to all direct and indirect annotations to double-strand break repair via alternative nonhomologous end joining (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for double-strand break repair via alternative nonhomologous end joining (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
double-strand break repair via alternative nonhomologous end joining	is_a	double-strand break repair via nonhomologous end joining (GO:0006303)

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