Term Information

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Accession
GO:0098535
Name
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
Ontology
biological_process
Synonyms
de novo centriole assembly via deuterosome, centriole amplification, deuterosomal basal body biogenesis, deuterosome pathway, deuterosome-mediated centriole biogenesis, multiciliation, multiciliogenesis, de novo centriole assembly
Alternate IDs
None
Definition
Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation. Source: PMID:5111878, GOC:cilia, PMID:24075808, GOC:dos, PMID:5661997
Comment
In most eukaryotic cells, 'centriole' (GO:0005814) and 'ciliary basal body' (GO:0036064) represent a common entity that cycles through its function in cell division, then ciliogenesis, then cell division again. However, these structures are modified extensively as they transition into each other, and may contain different proteins, specific to each component.
History
See term history for GO:0098535 at QuickGO
Chem. react.
has participant deuterosome
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0098535 from QuickGO

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Parents of de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (GO:0098535)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [RO:0000057 relation] RO:0000057  deuterosome (GO:0098536)
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [BFO:0000050 relation] BFO:0000050  multi-ciliated epithelial cell differentiation (GO:1903251)
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [is_a relation] is_a  de novo centriole assembly (GO:0097742)
de novo centriole assembly involved in multi-ciliated epithelial cell differentiation [RO:0002162 relation] RO:0002162  Metazoa (NCBITaxon:33208)

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