GO logo AmiGO 2

4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP

Term Information

Feedback 
Accession
GO:0106344
Name
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP
Ontology
molecular_function
Synonyms
None
Alternate IDs
None
Definition
Catalysis of the reaction: 2 Fe(3+) + 4 H2O + L-histidyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + N(6)-(pyridoxal phosphate)-L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] = (2S)-2-amino-5-hydroxy-4-oxopentanoyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase] + 3-oxopropanoate + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 2 Fe(2+) + 2 H+ + L-lysyl-[4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase]. Source: PMID:22568620, RHEA:65756
Comment
None
History
See term history for GO:0106344 at QuickGO
Chem. react.
has participant 3-oxopropanoate
has participant 4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-)
has participant iron(3+)
has participant water
has participant N(6)-(pyridoxal phosphate)-L-lysine(2-) residue
has participant iron(2+)
has participant hydron
has participant (2S)-2-amino-5-hydroxy-4-oxopentanoate residue
has participant L-lysinium residue
has participant L-histidine residue
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

Loading...
pending...
View this term in QuickGO.

Graph of GO:0106344 from QuickGO

Additional external viewing options
Additional internal viewing options
Parents of 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP (GO:0106344)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  3-oxopropanoate (CHEBI:33190)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  4-amino-2-methyl-5-phosphonatooxymethylpyrimidine(2-) (CHEBI:58354)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  iron(3+) (CHEBI:29034)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  water (CHEBI:15377)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  N(6)-(pyridoxal phosphate)-L-lysine(2-) residue (CHEBI:143915)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  iron(2+) (CHEBI:29033)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  hydron (CHEBI:15378)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  (2S)-2-amino-5-hydroxy-4-oxopentanoate residue (CHEBI:157692)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  L-lysinium residue (CHEBI:29969)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [is_a relation] is_a  transferase activity (GO:0016740)
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity from histidine and PLP [RO:0000057 relation] RO:0000057  L-histidine residue (CHEBI:29979)

This term has no children.

RHEA
65756