AmiGO 2: Term Details for "carboxylesterase activity" (GO:0106435)

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Term Information

Accession: GO:0106435
Name: carboxylesterase activity
Ontology: molecular_function
Synonyms: ali-esterase activity, nonspecific carboxylesterase activity, B-esterase activity, alpha-carboxylesterase activity, cocaine esterase, procaine esterase, serine esterase activity, triacetin esterase, vitamin A esterase
Alternate IDs: None
Definition: Catalysis of the reaction: a carboxylic ester + H2O = a carboxylate + an alcohol + H+. Source: RHEA:21164
Comment: Note: This covers a broad range of specificity; also hydrolyzes vitamin A esters.
History: See term history for GO:0106435 at QuickGO
Chem. react.: has participant hydron; has participant carboxylic acid anion; has participant carboxylic ester; has participant alcohol; has participant water
Subset: None
Related: Link to all genes and gene products annotated to carboxylesterase activity (excluding "regulates").; Link to all direct and indirect annotations to carboxylesterase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for carboxylesterase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0052689 carboxylic ester hydrolase activity
GO:0106435 carboxylesterase activity

Parents of carboxylesterase activity (GO:0106435)

subject	relation	object
carboxylesterase activity	RO:0000057	hydron (CHEBI:15378)
carboxylesterase activity	RO:0000057	carboxylic acid anion (CHEBI:29067)
carboxylesterase activity	RO:0000057	carboxylic ester (CHEBI:33308)
carboxylesterase activity	RO:0000057	alcohol (CHEBI:30879)
carboxylesterase activity	RO:0000057	water (CHEBI:15377)
carboxylesterase activity	is_a	carboxylic ester hydrolase activity (GO:0052689)

This term has no children.

EC: 3.1.1.1
MetaCyc: CARBOXYLESTERASE-RXN
Reactome: R-HSA-9727567; R-HSA-9749647; R-HSA-9619024
RHEA: 21164