AmiGO 2: Term Details for "RNA polymerase II termination complex" (GO:0110103)

Term Information

Accession: GO:0110103
Name: RNA polymerase II termination complex
Ontology: cellular_component
Synonyms: TXT complex
Alternate IDs: None
Definition: A conserved protein complex capable of 5'-3' exoribonuclease activity. It is able to promote RNA polymerase II (RNAPII) transcription termination by degrading pre-mRNA from the newly formed 5' phosphorylated end. Source: PMID:25722373, GOC:lnp, PMID:23200120
Comment: In S. cerevisiae, this complex is formed by RAI1 and RAT1; in H. sapiens it is formed by Twi12, Xrn2 and Tan1.
History: See term history for GO:0110103 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RNA polymerase II termination complex (excluding "regulates").; Link to all direct and indirect annotations to RNA polymerase II termination complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA polymerase II termination complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
GO:0009058 biosynthetic process
GO:0044237 cellular metabolic process
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0008152 metabolic process
GO:0071704 organic substance metabolic process
GO:0048518 positive regulation of biological process
GO:0048522 positive regulation of cellular process
GO:0009893 positive regulation of metabolic process
GO:0044238 primary metabolic process
GO:0050789 regulation of biological process
GO:0009889 regulation of biosynthetic process
GO:0031323 regulation of cellular metabolic process
GO:0050794 regulation of cellular process
GO:0019222 regulation of metabolic process
UBERON:0000061 anatomical structure
GO:0044249 cellular biosynthetic process
GO:0005575 cellular_component
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:1901360 organic cyclic compound metabolic process
GO:1901576 organic substance biosynthetic process
GO:0009891 positive regulation of biosynthetic process
GO:0031325 positive regulation of cellular metabolic process
GO:0031326 regulation of cellular biosynthetic process
GO:0060255 regulation of macromolecule metabolic process
GO:0019219 regulation of nucleobase-containing compound metabolic process
GO:0080090 regulation of primary metabolic process
GO:0003824 catalytic activity
CL:0000000 cell
GO:0110165 cellular anatomical entity
GO:0016043 cellular component organization
GO:0071840 cellular component organization or biogenesis
GO:0010467 gene expression
GO:0016787 hydrolase activity
GO:0009059 macromolecule biosynthetic process
GO:0090304 nucleic acid metabolic process
GO:1901362 organic cyclic compound biosynthetic process
GO:0031328 positive regulation of cellular biosynthetic process
GO:0010604 positive regulation of macromolecule metabolic process
GO:0045935 positive regulation of nucleobase-containing compound metabolic process
GO:0010556 regulation of macromolecule biosynthetic process
GO:0051252 regulation of RNA metabolic process
GO:0016070 RNA metabolic process
GO:0022411 cellular component disassembly
GO:0006351 DNA-templated transcription
GO:0016788 hydrolase activity, acting on ester bonds
GO:0005622 intracellular anatomical structure
GO:0003674 molecular_function
GO:0141187 nucleic acid biosynthetic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0043226 organelle
GO:0010557 positive regulation of macromolecule biosynthetic process
GO:0051254 positive regulation of RNA metabolic process
GO:0032984 protein-containing complex disassembly
GO:0043933 protein-containing complex organization
GO:0051128 regulation of cellular component organization
GO:0010468 regulation of gene expression
GO:2001141 regulation of RNA biosynthetic process
GO:0032774 RNA biosynthetic process
GO:0005488 binding
GO:0140098 catalytic activity, acting on RNA
GO:0006353 DNA-templated transcription termination
GO:0004527 exonuclease activity
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0043229 intracellular organelle
GO:0043227 membrane-bounded organelle
GO:0004518 nuclease activity
GO:0051130 positive regulation of cellular component organization
GO:1902680 positive regulation of RNA biosynthetic process
GO:0006355 regulation of DNA-templated transcription
GO:0043244 regulation of protein-containing complex disassembly
GO:0140640 catalytic activity, acting on a nucleic acid
GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0043231 intracellular membrane-bounded organelle
GO:0097159 organic cyclic compound binding
GO:0045893 positive regulation of DNA-templated transcription
GO:0043243 positive regulation of protein-containing complex disassembly
GO:0032991 protein-containing complex
PR:000050567 protein-containing material entity
GO:0031554 regulation of termination of DNA-templated transcription
GO:0004532 RNA exonuclease activity
GO:0004540 RNA nuclease activity
GO:0006369 termination of RNA polymerase II transcription
GO:0006366 transcription by RNA polymerase II
GO:0008409 5'-3' exonuclease activity
GO:1902494 catalytic complex
GO:0003676 nucleic acid binding
GO:0005634 nucleus
GO:0060566 positive regulation of termination of DNA-templated transcription
GO:0016462 pyrophosphatase activity
GO:1904594 regulation of termination of RNA polymerase II transcription
GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters
GO:0004534 5'-3' RNA exonuclease activity
GO:1905354 exoribonuclease complex
GO:0034353 mRNA 5'-diphosphatase activity
GO:0140513 nuclear protein-containing complex
GO:1904595 positive regulation of termination of RNA polymerase II transcription
GO:0003723 RNA binding
GO:0110103 RNA polymerase II termination complex

Parents of RNA polymerase II termination complex (GO:0110103)

subject	relation	object
RNA polymerase II termination complex	RO:0002215	mRNA 5'-diphosphatase activity (GO:0034353)
RNA polymerase II termination complex	RO:0002215	RNA binding (GO:0003723)
RNA polymerase II termination complex	is_a	nuclear protein-containing complex (GO:0140513)
RNA polymerase II termination complex	is_a	exoribonuclease complex (GO:1905354)
RNA polymerase II termination complex	RO:0002215	5'-3' RNA exonuclease activity (GO:0004534)
RNA polymerase II termination complex	RO:0002216	positive regulation of termination of RNA polymerase II transcription (GO:1904595)

This term has no children.

GONUTS Add usage comments for this term on the GONUTS wiki.