AmiGO 2: Term Details for "RNA NAD-cap (NMN-forming) hydrolase activity" (GO:0110153)

Accession: GO:0110153
Name: RNA NAD-cap (NMN-forming) hydrolase activity
Ontology: molecular_function
Synonyms: None
Alternate IDs: None
Definition: Catalysis of the reaction: a 5'-end NAD+-phospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-adenosine-phospho-ribonucleoside in mRNA + beta-nicotinamide D-ribonucleotide + 2 H+. Source: GOC:sp, PMID:31101919, RHEA:60876, PMID:25533955
Comment: This reaction specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.
History: See term history for GO:0110153 at QuickGO
Chem. react.: has participant hydron; has participant 5'-end NAD-phospho-ribonucleoside residue; has participant water; has participant 5'-end phospho-adenosine-phospho-ribonucleoside(3-) residue; has participant NMN(-)
Subset: None
Related: Link to all genes and gene products annotated to RNA NAD-cap (NMN-forming) hydrolase activity (excluding "regulates").; Link to all direct and indirect annotations to RNA NAD-cap (NMN-forming) hydrolase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA NAD-cap (NMN-forming) hydrolase activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

subject	relation	object
RNA NAD-cap (NMN-forming) hydrolase activity	RO:0000057	hydron (CHEBI:15378)
RNA NAD-cap (NMN-forming) hydrolase activity	RO:0000057	5'-end NAD-phospho-ribonucleoside residue (CHEBI:144029)
RNA NAD-cap (NMN-forming) hydrolase activity	RO:0000057	water (CHEBI:15377)
RNA NAD-cap (NMN-forming) hydrolase activity	is_a	catalytic activity, acting on RNA (GO:0140098)
RNA NAD-cap (NMN-forming) hydrolase activity	is_a	pyrophosphatase activity (GO:0016462)
RNA NAD-cap (NMN-forming) hydrolase activity	RO:0000057	5'-end phospho-adenosine-phospho-ribonucleoside(3-) residue (CHEBI:144051)
RNA NAD-cap (NMN-forming) hydrolase activity	RO:0000057	NMN(-) (CHEBI:14649)

This term has no children.