AmiGO 2: Term Details for "ubiquitin-modified protein reader activity" (GO:0140036)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0140036
Name: ubiquitin-modified protein reader activity
Ontology: molecular_function
Synonyms: ubiquitin-dependent protein binding
Alternate IDs: None
Definition: A molecular adaptor recognizes and binds a target protein containing a ubiquitination modification and brings the target protein into contact with another protein to allow those proteins to function in a coordinated way. Source: PMID:26060076
Comment: This term should only be used when the binding is shown to require ubiquitination of the target protein: the interaction needs to be tested with and without the PTM. The binding does not need to be at the site of ubiquitination. It may be that the ubiquitination causes a conformational change that allows binding of the protein to another region; this type of ubiquitination-dependent protein binding is valid for annotation to this term.
History: See term history for GO:0140036 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to ubiquitin-modified protein reader activity (excluding "regulates").; Link to all direct and indirect annotations to ubiquitin-modified protein reader activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for ubiquitin-modified protein reader activity (excluding "regulates").